Dolomite is a world leader in solving Microfluidic problems. Microfluidics, also known as “lab-on-a-chip” is an emerging technology that is beginning to shape the future of many drug discovery processes. Microfluidics enables small scale fluid control and analysis, allowing manufacturers, institutions and end users to develop smaller, more cost-effective, and more powerful systems.
Dolomite has innovative, world class engineering and microfabrication capabilities and is able to provide either standard solutions or custom designs for devices, sub-systems and instruments for a broad spectrum of customer applications.
Dolomite as a world leader in microfluidics is keen to work with partners in a wide range of application areas relating to the control and measurement of fluids at a microscale and is focused on delivering "real world" solutions for customers.
For more information regarding Dolomite products please click on www.dolomite-microfluidics.com or if you would like to discuss the dolomite products for a specific application in medicinal chemistry please contact Kelvin@flowtrek.com or call 607 351 7742.
Syrris creates automated products for research and development chemists and is a world leader in flow chemistry, and automation technology. Syrris products are used in a wide variety of applications and laboratories including process, discovery, crystallization, process safety, scale-up and many more.
The FRX system from Syrris is a cost effective, intuitive and scalable option for medicinal chemists considering exploring flow chemistry as an alternative to conventional or microwave synthesis. Made up of a number of modules the FRX can form simple yet powerful flow chemistry systems.
From the introductory FRX 100 to the FRX 400 offering the widest range of reaction scale of all options.
FRX Benefits
- Faster reactions: Increase reaction rates over 100 fold
by superheating reactions significantly above reflux e.g. dichloromethane to 100°C, acetonitrile to 150°C and water to 170°C. - Cleaner reactions: Reduced impurities via excellent, reproducible reaction control and optional use of solid phase reagents/catalysts/scavengers.
- Inline aqueous work-up: The Flow Liquid Liquid
Extraction Module (FLLEX) enables two immiscible phases to be mixed and separated in flow, immediately following the reaction. - Safer reactions: Only small amounts of material react at any time, minimizing exotherms and the quantity of any hazardous intermediates.
- Rapid development: Reaction time, temperature and equivalents can be rapidly varied using mg of substrate.
- Scale-up: Production rates up to kg overnight. Wide temperature range: Heat reactions up to 200°C or cool down to -20°C.
- Chemically resistant: Glass and PTFE reactors allow a wide range of chemistry.
- Compact size: FRX systems fit easily into standard fume cupboards.
